Magic Mushrooms and Depression

Arih Feb 09, 2022
Magic Mushrooms and Depression

Depression is being talked about more than ever and rightfully so. But many of us still have no idea how to address it. No matter how many mental health accounts and #positiveaffirmations hashtags we follow on Instagram, our lizard brain — that nagging voice in our head — makes us feel like our entire world is falling apart.

That’s because depression isn’t what you think. It’s not just a disorder you can write off, get some pills for and “cure” overnight. It also isn’t something that exists entirely in your head. There is real neuroscience that supports the depression-as-a-chemical-imbalance theory (though that isn’t as concrete as you might think, either.) 

So, if you follow any online conversations around mental health, you’ve definitely heard about magic mushrooms and how it’s used to treat depression. If not, that’s okay. We’re going to fill you in on all the details. It turns out there’s a lot of compelling research to support the efficacy of microdosing mushrooms for depression. 

This doesn’t mean you should run out and start taking shrooms on the daily, though. Any magic mushroom treatment for depression should get the green light from your doctor, therapist and psychiatrist (if applicable). 

Let’s start off with the basics. 

How Do Magic Mushroom Help Depression?

What exactly makes them magic? When you think of someone taking shrooms, you probably imagine seizure inducing lights illuminating a sea of people in beaded crop-tops at Coachella. Or maybe a new age yogi who who took too much shrooms at Burning Man and claims to have found the meaning of life.

As it turns out, there’s no magic here. It’s science (*Cue Bill Nye theme song*). Magic mushrooms contain a psychedelic drug called psilocybin. Psilocybin naturally occurs in over 200 species of fungi, and has recently undergone serious medical evaluation as a potential treatment for mental health issues, namely depression and anxiety. 

2021 psilocybin depression study found that it worked faster and more effectively than the prescription antidepressant Lexapro. The study was led by Robert Carhart-Harris, PhD, director of the Centre for Psychedelic Research at Imperial College London. 

In a six-week trial of 59 patients with moderate-to-severe depression, there was no noticeable difference between high-dose psilocybin and Lexapro. SSRIs (Selective serotonin reuptake inhibitors) have been the go-to treatment for depression for decades, but a lot of people are coming clean and admitting they never really worked as well as they hoped. 

This doesn’t mean magic mushrooms are the perfect solution, either. Depression doesn’t always make sense, and everyone’s ideal treatment will differ. That being said, promising research and real experiences circulating around the web are showing that psilocybin for depression could help a lot of people.

How Magic Mushrooms Affect the Brain

Just like a prescription antidepressant, shrooms are all about serotonin. They help build and strengthen neural pathways that open your mind to greater potential. Depression can create shortcuts to negative thinking, which send us spiraling into bouts of self-doubt and loathing.

These negative thought patterns become habitual, and it’s why you may think you are the root of the problem even though that’s not the case.

Depression can be brutally persistent and shrooms can help open up doors you didn’t see before. They can help you feel more open-minded, and as a result, more hopeful and optimistic. 

For someone who’s been wrestling with depression for years, darkness feels endless. Eventually, you may even resign yourself to thinking this is all there is for you. That’s not true, and it never has been.

We can’t say shrooms are for everyone, but they do benefit a lot of people. So much so, in fact, that major hospitals and research teams are now looking into them as a viable clinical treatment option. 

To comment please sign in.

anonymous*77444 says May 14, 2024, 8:05 pm

I'm depressed; give me free mushrooms

anonymous*89193 says May 4, 2024, 5:01 am

Helped me so much

Malik J says April 1, 2024, 9:34 am


anonymous*103800 says March 6, 2024, 11:41 am


anonymous*96068 says January 24, 2024, 3:48 am

I'm always depressed and it sucks

anonymous*96794 says January 23, 2024, 10:33 am

Sometimes I'm depressed :(

anonymous*92317 says December 20, 2023, 11:00 pm

microdosing bc medications just weren't working for me!

anonymous*92317 says December 16, 2023, 11:57 pm

shrooms definitely help me see doors I didn't know were there before

anonymous*78357 says November 13, 2023, 11:23 pm

Great stuff. Learned alot!

anonymous*86187 says November 9, 2023, 7:35 pm

This is for real!

anonymous*86187 says November 8, 2023, 1:13 pm

Amazing info here

anonymous*86187 says November 7, 2023, 11:35 pm

This is good

anonymous*86187 says November 6, 2023, 8:00 pm

Love this!

anonymous*86187 says November 6, 2023, 7:47 pm

Great info here

anonymous*86187 says October 31, 2023, 4:40 pm

This is awesome

anonymous*78357 says October 20, 2023, 12:29 am

most helpful!

Matt H says September 12, 2023, 4:32 pm

I've lived my entire life with Depression and Anxiety. A couple of years ago I weened myself off my medication which was brutal. I bear knuckled it for a couple of years. I was on the brink of being suicidal. Last year I signed up for TMS treatment (which is a big magnet) it cured my depression and did zero for my anxiety. So I started ketamine treatment two months after. I helped with my anxiety a lot yet still persisted. I did a hero dose with one of your chocolate bars and for the first time in my life no anxiety.

Want to read more entries?